Phosphatase tensin-type
WebPhospatase and tensin homolog (PTEN) is a protein phosphatase involved in cell polarization and directed movement, neurogenesis, glucose and metabolism. Its role as a lipid phosphatase is critical for its role in tumor suppression, and mutations in PTEN are associated with the development of many cancers. WebKey features and details Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply Rabbit monoclonal [EPR9941-2] to PTEN Suitable for: Flow Cyt (Intra), IHC-P, WB Knockout validated Reacts with: Mouse, Rat, Human Related conjugates and formulations Carrier Free HRP You may also be interested in
Phosphatase tensin-type
Did you know?
WebMethods: Human renal biopsies, histopathologically categorized as normal, early Type 2 diabetes mellitus (T2DM), or established DN, were analyzed for the localization and expression of IGF2, its negative regulator phosphatase and tensin homolog on chromosome 10 (PTEN), and SPARC. WebMay 2, 2024 · PDM [PtdIns (4,5)P 2 -binding motif], Ptase (Phosphatase tensin-type domain), C2 (C2 tensin-type domain), DUF547 (Domain of unknown function), PDZ-BM (PDZ-binding motif), PEST (proline, glutamine, serine, threonine sequence), red triangle indicates the nuclear localization sequence.
WebAug 22, 2024 · Background: Phosphatase and tensin homolog (PTEN) is an important tumor suppressor gene, and its encoded protein has activities of both a protein phosphatase and a lipid phosphatase. However, the substitution effect of protein phosphatase activity remains unclear. PI3K/Akt is the most common pathway negatively regulated by PTEN. WebPhosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a lipid phosphatase implicated in cellular proliferation and survival. In animal cells, loss of PTEN leads to increased levels of phosphatidylinositol (3,4,5)-trisphosphate, stimulation of glucose and lipid metabolism, cellular growth, and morphological changes (related to adaptation and …
Webphosphatase and tensin homolog. Synonyms. 2310035O07Rik, A130070J02Rik, B430203M17Rik, MMAC1, TEP1. Feature Type. protein coding gene. IDs. MGI:109583. … Phosphatase and tensin homolog (PTEN) is a phosphatase in humans and is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers, specifically glioblastoma, lung cancer, breast cancer, and prostate cancer. Genes corresponding to PTEN (orthologs) have been identified in most mammals for which complete genome data are available.
WebDescription: Homo sapiens transmembrane phosphatase with tensin homology (TPTE), transcript variant 1, mRNA. (from RefSeq NM_199261) RefSeq Summary (NM_199261): …
WebChromatin immunoprecipitation showed that wild-type PTMA protein binds to the PTEN promoter and enhances phosphatase and tensin homolog (PTEN) expression. Through immunoblot proteomics and in vivo ubiquitination studies, PTMA protein can bind with tripartite motif-containing protein 21 (TRIM21) and block its ubiquitination. healthy gatorade recipeWebDESCRIPTION:RecName: Full=Putative tyrosine-protein phosphatase TPTE; EC=3.1.3.48; AltName: Full=Cancer/testis antigen 44; Short=CT44; AltName: Full=Transmembrane phosphatase with tensin homology; AltName: Full=Tumor antigen BJ-HCC-5; FUNCTION:Could be involved in signal transduction. motorway hullWebMay 15, 2024 · Muscle-specific expression of the RNA-binding protein Staufen1 induces progressive skeletal muscle atrophy via regulation of phosphatase tensin homolog Converging lines of evidence have now highlighted the key role for post-transcriptional regulation in the neuromuscular system. motorway improvementsWebAug 21, 2024 · PTEN (PHOSPHATASE AND TENSIN HOMOLOG) (EG, COWDEN SYNDROME, PTEN HAMARTOMA TUMOR SYNDROME) GENE ANALYSIS; DUPLICATION/DELETION VARIANT 81351 TP53 (TUMOR PROTEIN 53) (EG, LI-FRAUMENI SYNDROME) GENE ANALYSIS; FULL GENE SEQUENCE ... Absence of a Bill Type does not guarantee that the … motorway how many lanesWebMay 3, 2024 · Phosphatase and tensin homolog (PTEN) is a tumor suppressor frequently mutated in diverse cancers. Germline PTEN mutations are also associated with a range of … motorway incidents todayWebKey features and details Rabbit polyclonal to PTEN Suitable for: IHC-P, WB Reacts with: Human Isotype: IgG Get better batch-to-batch reproducibility with a recombinant antibody Anti-PTEN antibody [EPR9941-2] (ab170941) Research with confidence – consistent and reproducible results with every batch motorway illustrationWebJun 1, 2024 · The Phosphatase and tensin homolog (PTEN) gene is one of the most important tumor suppressor genes, which acts through its unique protein phosphatase … motorway industrial park