Klf2 colon

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August undefined, 2024

WebJan 17, 2024 · KLF2 is critical to maintaining endothelial barrier integrity and preventing gap formations and in prevention of glomerular endothelial cell and podocyte damage in diabetic mice. KLF4 is renoprotective in the setting of AKI and is a critical regulator of proteinuria in mice and humans. WebKLF2/4 Antibody (BS-1064R) in IHC (P) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Rabbit Anti KLF4 Polyclonal Antibody, Unconjugated (bs-1064R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Product Details Target Information Transcription factor; can act both as activator and as repressor.

Expression and Prognosis Value of the KLF Family Members in ... - Hindawi

WebJul 13, 2024 · Krüppel-like factor 2 (KLF2) is a potent regulator of lymphocyte differentiation, activation and migration. However, its functional role in adaptive and humoral immunity remains elusive. ... the blood and the lamina propria of the colon and the small intestine, concomitant with their accumulation and retention in mesenteric lymph nodes and ... WebApr 8, 2024 · In colon cells, CDX2 upregulated KLF4 by binding to KLF4 promoter and reducing the association of histone 3 lysine 4 trimethylation with KDM5B demethylase, and acting as a tumor suppressor. division 2 hunters fury build 2022

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WebMar 9, 2024 · However, reactive oxygen species (ROS) degradation of BH4 leads to eNOS inactivation causing EC dysfunction. miR-484 and miR-93 in ECs are able to target the seed sequence of the 3’UTR of eNOS and Krüppel-like factor 2 (KLF2) mRNAs and repress protein transcription (31, 55). The sustained low expression of miR-484 in ECs under … WebKLF2 Antibody (PA5-115479) in IHC (P) Immunohistochemistry analysis of KLF2 in human colorectal cancer and adjacent normal tissues. Samples were treated with formaldehyde … WebApr 7, 2016 · The functions of interleukin-17A (IL-17A) in adipose tissues and adipocytes have not been well understood. In the present study, male mice were fed with a regular diet (n = 6, lean mice) or a high-fat diet (n = 6, obese mice) for 30 weeks. Subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) were analyzed for IL-17A levels. SAT and … division 2 hunter set

Kruppel-like factor 2 mediated anti-proliferative and anti-metastasis …

Krϋppel-like factors (KLFs) in renal physiology and disease

WebAug 22, 2014 · KLF2-/ - colon ies are also smaller than wild-t ype, altho ugh. simil ar in size to KLF1-/-. It was of inter est to disti nguis h. whethe r there are few er than norm al progen itors in KLF1- WebOct 17, 2024 · Marginal zone lymphoma (MZL) is classified as a group of slow-growing, non-Hodgkin’s B-cell lymphomas. 1. Extranodal marginal zone B-cell lymphoma or mucosa-associated lymphoid tissue (MALT ... craftsman 4.5 lawn mower partsWebApr 25, 2006 · The mechanisms regulating activation of monocytes remain incompletely understood. Herein we provide evidence that Kruppel-like factor 2 (KLF2) inhibits … division 2 hunters fury gear set

"WebNov 18, 2024 · KLF2 regulates metaflammation transcription in macrophages RNA-sequencing of bone marrow-derived macrophages (BMDMs) isolated from myeloid-specific KLF2 knockout (K2KO) and control (LysM) mice... " - Klf2 colon

Klf2 colon

WebApr 13, 2024 · KLF2 expression levels were found to be reduced in advanced cancer stages and grades, while positively correlated with the expression of estrogen receptor (ER), progesterone receptor (PR), and tumor size in breast cancer, according to the Tumor Immune Estimation Resource and Human Protein Atlas databases. Background: As a … WebMay 10, 2004 · Endo-KLF2 refers to endogenous human KLF2. (B) KLF2 inhibits IL-1β–mediated induction of VCAM-1 and E-selectin protein levels. Experiments were performed as described in A except cells were harvested for total protein and Western blot analysis was performed. (C) KLF2 inhibits VCAM-1 and E-selectin in response to multiple …

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WebKLF2 protein expression summary - The Human Protein Atlas. KLF2. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. KLF2 INFORMATION. Proteini. Full … WebMar 19, 2024 · In colon cancer and rectal cancer, KLFs were also shown to be associated with a variety of immune cells. ... in CRC patients, we used various online analytic tools, including ONCOMINE, TCGA, cBioPortal, and the TIMER database. KLF2-6, KLF8-10, KLF12-15, and KLF17 mRNA expression levels were dramatically downregulated in CRC tissues, …

WebMay 5, 2004 · KLF2 Inhibits IL-1β–mediated Induction of Adhesion Molecules and T Cell Rolling and Adhesion to Endothelial Cells. ... The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development. 129:2619–2628. [PMC free article] [Google Scholar] 25. WebAug 23, 2024 · KLF2 was first identified in 1995, using the zinc finger region of erythroid Krüppel-like factor (EKLF, KLF1) as the hybridization probe ( Anderson et al., 1995 ), and first termed as lung Krüppel-like factor (LKLF), since it was found to be primarily expressed in lung ( Anderson et al., 1995 ).

WebMay 30, 2013 · Kruppel-like factors (KLFs) is a subclass of the zinc-finger family of transcription factors important in cell differentiation and growth. 6 KLF2 is highly expressed in vascular endothelium and orchestrates endothelium-dependent vascular homeostasis in health. 7, 8 KLF2 expression in the endothelium is upregulated by laminar shear stress … Web维普期中文期刊服务平台，由维普资讯有限公司出品，通过对国内出版发行的14000余种科技期刊、5600万篇期刊全文进行内容分析和引文分析，为专业用户提供一站式文献服务：全文保障，文献引证关系，文献计量分析；并以期刊产品为主线、其它衍生产品或服务做补充，方便专业用户、机构用户在 ...

WebMay 29, 2014 · Maturation as well as antigen-dependent activation of B cells is accompanied by alternating phases of proliferation and quiescence. We and others have …

WebMar 3, 2024 · MAP3K2 is a serine/threonine kinase belonging to the MAP3K superfamily 11. To investigate the role of MAP3K2 in the intestine, we added dextran sodium sulfate (DSS), which causes colitis, to the... craftsman 45 offset wrenchesWebApr 16, 2024 · In order to provide more evidences to illustrate the function of KLF2 in colon cancer, we obtain colon cancer patient tissues data from TCGA and analyzed the … craftsman 46cc chainsaw manualWebJan 17, 2024 · KLF2 is critical to maintaining endothelial barrier integrity and preventing gap formations and in prevention of glomerular endothelial cell and podocyte damage in … division 2 hunters missionWebApr 16, 2024 · The results showed that KLF2 might be a tumor suppressor gene in colon cancer, which was in accordance with our experimental data. We also found that CDKN1A expression in mutant p53 colon cancer tissue was significant decreased when compared with p53 wild type colon cancer tissue, while Wnt ligand Wnt5a exhibited the highest level … craftsman 45 in workbench with drawerWebApr 1, 2024 · Introduction. Krüppel-like factor 2 (KLF2), a zinc-finger transcription factor, is a crucial regulator of differentiation, proliferation and activation of various cell types, including T- and B-lymphocytes 1, 2, 3.Within the B cell lineage, KLF2 expression is induced during early B cell development in the bone marrow (BM) by signals of the pre-B cell receptor and … division 2 hunters masksWebKLF2, also known as lung Kruppel-like factor, is a 355 amino acid protein that is predominantly expressed in the lung, spleen, and heart tissue [19] ( Table 1 ). KLF4 also known as gut-enriched Kruppel-like factor or epithelial zinc finger, is a 470 amino acid protein that is centrally distributed in epithelial cells of the gastrointestinal tract. division 2 hunter\u0027s furyWebJun 6, 2024 · KLF2 expression is reduced in human CRC cell lines (SW480, HT29, SW620 and HCT116) compared with the normal human colon epithelial cells (FHC). (A) KLF2 mRNA expression was detected by RT-PCR assay. (B) Western blot analysis was used to measure KLF2 protein expression. craftsman 46cc backpack blower gas tank